专利名称：Method for field-based ecological risk
assessment using rodent sperm-analysis
发明人：Lawrence V. Tannenbaum申请号：US10820848申请日：20040409公开号：US07627434B2公开日：20091201
摘要：The invention is a method for assessing whether or not reproductive healtheffects are present in terrestrial ecological receptors inhabiting contaminated sites.Adult male rodents are concurrently trapped at the contaminated site of interest and ata matched non-contaminated reference location. In at least some embodiments, thesperm analysis can be corroborated with additional data to further increase the accuracyof the comparison. For a given small rodent species, three sperm parameters, all of whichare barometers of reproductive success (a high concern ecological risk assessmenttoxicological endpoint), are compared in the animals trapped at the contaminated siteand the animals trapped at the reference location. Where one or more of the spermparameter thresholds are exceeded in the site rodents, and the difference is found to bestatistically significant, the interpretation is that site terrestrial receptors are beingreproductively compromised.
申请人：Lawrence V. Tannenbaum
地址：Baltimore MD US
国籍：US
代理人：Elizabeth Arwine
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