HOPO CHELATORS

专利名称：HOPO CHELATORS

发明人：Butlin, Nathaniel, G.,Raymond, Kenneth,

N.,Xu, Jide,D'Aleo, Anthony

申请号：EP14178387.8申请日：20100824公开号：EP2816038B1公开日：20191120

摘要：The present invention provides a novel class of macrocyclic compounds offormula (I) as well as complexes formed between a metal (e.g., lanthanide) ion and thecompounds of the invention. Preferred complexes exhibit high stability as well as highquantum yields of lanthanide ion luminescence in aqueous media without the need forsecondary activating agents. Preferred compounds comprise hydroxypyridinonyl moietieswithin their macrocyclic structure and are characterized by surprisingly low, non-specificbinding to a variety of polypeptides such as antibodies and proteins as well as high kineticstability. (I)

代理机构：HGF Limited

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