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Mammalian alpha-kinase proteins, nucleic acids and

2020-02-09 来源:汇智旅游网
专利内容由知识产权出版社提供

专利名称:Mammalian alpha-kinase proteins, nucleic

acids and diagnostic and therapeutic usesthereof

发明人:Alexey Ryazanov申请号:US11496050申请日:20060728

公开号:US20070184043A1公开日:20070809

摘要:The present invention provides novel mammalian alpha-kinase proteins:melanoma alpha-kinase (MK), heart alpha-kinase (HK), kidney alpha-kinase (KK), skeletalmuscle alpha-kinase (SK), and lymphocyte alpha-kinase (LK). In particular, a novel kinasetype is herein provided, characterized by the presence of an alpha-kinase catalyticdomain and an ion channel domain. Isolated nucleic acids of the alpha-kinases MK, HK, KK,SK and LK are provided. Methods for making the novel alpha-kinases, cells that expressthe alpha-kinases and methods for treating an animal in need of either increased ordecreased activity of the alpha- kinases are provided.

申请人:Alexey Ryazanov

地址:Princeton NJ US

国籍:US

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